N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide
TL;DR: N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide (CAS 5548-83-4) is a chemical compound with molecular formula C12H8ClFN2O and molecular weight 250.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide
Also Known As: MixCom6_001031, N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide, BIM-0024029.P001, N-(3-chloro-4-fluorophenyl)isonicotinamide, N-(3-chloro-4-fluorophenyl)-4-pyridylcarboxamide
| Molecular Formula | C12H8ClFN2O |
|---|---|
| Molecular Weight | 250.03 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 42.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 250.03091 |
| Heavy Atoms | 17 |
| Complexity | 271.0 |
Chemical Identifiers
| CAS Number | 5548-83-4 |
|---|---|
| SMILES | C1=CC(=C(C=C1NC(=O)C2=CC=NC=C2)Cl)F |
| InChIKey | QVVFZIJFXFRWNP-UHFFFAOYSA-N |
Product Overview
N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide (CAS 5548-83-4), with molecular formula C12H8ClFN2O and molecular weight 250.03 g/mol. IUPAC: N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide.
Chemical Property Profile of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide
Property Insights of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide. With a topological polar surface area (TPSA) of 42.0 Ų, N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide?
The CAS number of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide is 5548-83-4.
What is the molecular formula of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide?
The molecular formula of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide is C12H8ClFN2O.
What is the molecular weight of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide?
The molecular weight of N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide is 250.03 g/mol.
Where can I buy N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide?
You can request a quote for N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-chloro-4-fluorophenyl)pyridine-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.