Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio structure

Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio

TL;DR: Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio (CAS 55477-27-5) is a chemical compound with molecular formula C12H20ClN5OS and molecular weight 317.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[4-[6-chloro-2-(methylamino)-5-methylsulfanylpyrimidin-4-yl]piperazin-1-yl]ethanol

Also Known As: 5-25-12-00572 (Beilstein Handbook Reference), Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio, 4-Chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthiopyrimidine, 2-Methylamino-4-N-(beta-hydroxyethyl)-piperazino-6-chloro-5-methylthio-pyrimidine, 2-[4-[6-chloro-2-(methylamino)-5-methylsulfanylpyrimidin-4-yl]piperazin-1-yl]ethanol

CAS: 55477-27-5
Molecular Formula C12H20ClN5OS
Molecular Weight 317.11 g/mol
LogP 1.6
Topological Polar Surface Area 89.8 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 317.1077
Heavy Atoms 20
Complexity 293.0

Chemical Identifiers

CAS Number 55477-27-5
SMILES CNC1=NC(=C(C(=N1)Cl)SC)N2CCN(CC2)CCO
InChIKey RGXCCTUBFMDKJO-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio (CAS 55477-27-5), with molecular formula C12H20ClN5OS and molecular weight 317.11 g/mol. IUPAC: 2-[4-[6-chloro-2-(methylamino)-5-methylsulfanylpyrimidin-4-yl]piperazin-1-yl]ethanol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio

XLogP
1.6
TPSA (Topological Polar Surface Area)
89.8
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
20
Complexity
293.0
Exact Mass
317.1077
Monoisotopic Mass
317.1077
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio

The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio. The TPSA of 89.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio. Following Lipinski's Rule of Five, Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio?

The CAS number of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio is 55477-27-5.

What is the molecular formula of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio?

The molecular formula of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio is C12H20ClN5OS.

What is the molecular weight of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio?

The molecular weight of Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio is 317.11 g/mol.

Where can I buy Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio?

You can request a quote for Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio?

Yes, KEHONG BIO provides custom synthesis services for Pyrimidine, 4-chloro-6-(2-hydroxyethylpiperazino)-2-methylamino-5-methylthio and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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