5-fluorouridine triacetate
TL;DR: 5-fluorouridine triacetate (CAS 55474-11-8) is a chemical compound with molecular formula C15H17FN2O9 and molecular weight 388.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,3R,4R,5R)-3,4-diacetyloxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
Also Known As: 5-fluorouridine triacetate, 2 -O,3 -O,5 -O-Triacetyl-5-fluorouridine, 5-Fluoro-2 -O,3 -O,5 -O-triacetyluridine, 4-(acetyloxy)-2-[(acetyloxy)methyl]-5-(5-fluoro-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)tetrahydro-3-furanyl acetate, 1-(2-O,3-O,5-O-Triacetyl-beta-D-ribofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
| Molecular Formula | C15H17FN2O9 |
|---|---|
| Molecular Weight | 388.09 g/mol |
| LogP | -1.0004 |
| Topological Polar Surface Area | 142.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 388.0918 |
| Heavy Atoms | 27 |
| Complexity | 861.5789 |
Chemical Identifiers
| CAS Number | 55474-11-8 |
|---|---|
| SMILES | CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)OC(=O)C)OC(=O)C |
Product Overview
5-fluorouridine triacetate (CAS 55474-11-8), with molecular formula C15H17FN2O9 and molecular weight 388.09 g/mol. IUPAC: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate.
Chemical Property Profile of 5-fluorouridine triacetate
Property Insights of 5-fluorouridine triacetate
The XLogP value of -1.0004 indicates that 5-fluorouridine triacetate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 142.99 Ų indicates high polarity, suggesting 5-fluorouridine triacetate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-fluorouridine triacetate has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-fluorouridine triacetate?
The CAS number of 5-fluorouridine triacetate is 55474-11-8.
What is the molecular formula of 5-fluorouridine triacetate?
The molecular formula of 5-fluorouridine triacetate is C15H17FN2O9.
What is the molecular weight of 5-fluorouridine triacetate?
The molecular weight of 5-fluorouridine triacetate is 388.09 g/mol.
Where can I buy 5-fluorouridine triacetate?
You can request a quote for 5-fluorouridine triacetate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-fluorouridine triacetate?
Yes, KEHONG BIO provides custom synthesis services for 5-fluorouridine triacetate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.