Lotucaine
TL;DR: Lotucaine (CAS 55122-20-8) is a chemical compound with molecular formula C18H29NO2 and molecular weight 291.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2-methylphenoxy)-3-(2,2,5,5-tetramethylpyrrolidin-1-yl)propan-2-ol
Also Known As: Lotucaine, Lotucaina, Lotucainum, Lotucaine, (+)-, Lotucaine, (-)-
| Molecular Formula | C18H29NO2 |
|---|---|
| Molecular Weight | 291.22 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 32.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 291.21982 |
| Heavy Atoms | 21 |
| Complexity | 324.0 |
Chemical Identifiers
| CAS Number | 55122-20-8 |
|---|---|
| SMILES | CC1=CC=CC=C1OCC(CN2C(CCC2(C)C)(C)C)O |
| InChIKey | ALJMIOMYHUNJQX-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lotucaine (CAS 55122-20-8), with molecular formula C18H29NO2 and molecular weight 291.22 g/mol. IUPAC: 1-(2-methylphenoxy)-3-(2,2,5,5-tetramethylpyrrolidin-1-yl)propan-2-ol.
Chemical Property Profile of Lotucaine
Property Insights of Lotucaine
The XLogP value of 3.9 indicates that Lotucaine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.7 Ų, Lotucaine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lotucaine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lotucaine?
The CAS number of Lotucaine is 55122-20-8.
What is the molecular formula of Lotucaine?
The molecular formula of Lotucaine is C18H29NO2.
What is the molecular weight of Lotucaine?
The molecular weight of Lotucaine is 291.22 g/mol.
Where can I buy Lotucaine?
You can request a quote for Lotucaine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lotucaine?
Yes, KEHONG BIO provides custom synthesis services for Lotucaine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.