(2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide
TL;DR: (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide (CAS 549489-72-7) is a chemical compound with molecular formula C13H10FNOS and molecular weight 247.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(3-fluorophenyl)-3-thiophen-2-ylprop-2-enamide
Also Known As: (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide, (E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)acrylamide, (E)-N-(3-fluorophenyl)-3-thiophen-2-ylprop-2-enamide, (2E)-N-(3-fluorophenyl)-3-(2-thienyl)prop-2-enamide, F1736-0598
| Molecular Formula | C13H10FNOS |
|---|---|
| Molecular Weight | 247.05 g/mol |
| LogP | 3.5391 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 247.0467 |
| Heavy Atoms | 17 |
| Complexity | 534.1123 |
Chemical Identifiers
| CAS Number | 549489-72-7 |
|---|---|
| SMILES | C1=CC(=CC(=C1)F)NC(=O)/C=C/C2=CC=CS2 |
Product Overview
(2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide (CAS 549489-72-7), with molecular formula C13H10FNOS and molecular weight 247.05 g/mol. IUPAC: (E)-N-(3-fluorophenyl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide
Property Insights of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide
The XLogP value of 3.5391 indicates that (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide?
The CAS number of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide is 549489-72-7.
What is the molecular formula of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide?
The molecular formula of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide is C13H10FNOS.
What is the molecular weight of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide?
The molecular weight of (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide is 247.05 g/mol.
Where can I buy (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide?
You can request a quote for (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-N-(3-fluorophenyl)-3-(thiophen-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.