Isorotenone structure

Isorotenone

TL;DR: Isorotenone (CAS 549-22-4) is a chemical compound with molecular formula C23H22O6 and molecular weight 394.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1S,13S)-16,17-dimethoxy-6-propan-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14,16,18-heptaen-12-one

Also Known As: Isorotenone, Sclerotiorin, Spectrum2_000209, Spectrum3_000155, Spectrum4_001482

CAS: 549-22-4
Molecular Formula C23H22O6
Molecular Weight 394.14 g/mol
LogP 4.6933
Topological Polar Surface Area 67.13 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 3
Exact Mass 394.14163
Heavy Atoms 29
Complexity 1126.0887

Chemical Identifiers

CAS Number 549-22-4
SMILES CC(C)C1=CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC

Product Overview

Isorotenone (CAS 549-22-4), with molecular formula C23H22O6 and molecular weight 394.14 g/mol. IUPAC: (1S,13S)-16,17-dimethoxy-6-propan-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14,16,18-heptaen-12-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Isorotenone

XLogP
4.6933
TPSA (Topological Polar Surface Area)
67.13
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
3
Heavy Atoms
29
Complexity
1126.0887
Exact Mass
394.14163
Monoisotopic Mass
394.14163
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Isorotenone

The XLogP value of 4.6933 indicates that Isorotenone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.13 Ų falls within the moderate polarity range, balancing permeability and solubility for Isorotenone. Following Lipinski's Rule of Five, Isorotenone has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Isorotenone?

The CAS number of Isorotenone is 549-22-4.

What is the molecular formula of Isorotenone?

The molecular formula of Isorotenone is C23H22O6.

What is the molecular weight of Isorotenone?

The molecular weight of Isorotenone is 394.14 g/mol.

Where can I buy Isorotenone?

You can request a quote for Isorotenone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Isorotenone?

Yes, KEHONG BIO provides custom synthesis services for Isorotenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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