1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine
TL;DR: 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine (CAS 548778-74-1) is a chemical compound with molecular formula C20H20Cl2N2O4 and molecular weight 422.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(5-chloro-2-methoxybenzoyl)piperazin-1-yl]-(5-chloro-2-methoxyphenyl)methanone
Also Known As: 1,4-BIS(5-CHLORO-2-METHOXYBENZOYL)PIPERAZINE, [4-(5-chloro-2-methoxy-benzoyl)piperazin-1-yl]-(5-chloro-2-methoxy-phenyl)methanone, [4-(5-chloro-2-methoxybenzoyl)piperazin-1-yl]-(5-chloro-2-methoxyphenyl)methanone, 669-216-6, RefChem:416438
| Molecular Formula | C20H20Cl2N2O4 |
|---|---|
| Molecular Weight | 422.08 g/mol |
| LogP | 3.6088 |
| Topological Polar Surface Area | 59.08 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 422.08002 |
| Heavy Atoms | 28 |
| Complexity | 822.2696 |
Chemical Identifiers
| CAS Number | 548778-74-1 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)Cl)C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)Cl)OC |
Product Overview
1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine (CAS 548778-74-1), with molecular formula C20H20Cl2N2O4 and molecular weight 422.08 g/mol. IUPAC: [4-(5-chloro-2-methoxybenzoyl)piperazin-1-yl]-(5-chloro-2-methoxyphenyl)methanone.
Chemical Property Profile of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine
Property Insights of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine
The XLogP value of 3.6088 indicates that 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.08 Ų, 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine?
The CAS number of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine is 548778-74-1.
What is the molecular formula of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine?
The molecular formula of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine is C20H20Cl2N2O4.
What is the molecular weight of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine?
The molecular weight of 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine is 422.08 g/mol.
Where can I buy 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine?
You can request a quote for 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1,4-Bis(5-chloro-2-methoxybenzoyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.