Loxapine Hydrochloride
TL;DR: Loxapine Hydrochloride (CAS 54810-23-0) is a chemical compound with molecular formula C18H19Cl2N3O and molecular weight 363.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine;hydrochloride
Also Known As: Loxapine hydrochloride, Loxapine HCl, Loxitane IM, LOXITANE C, Desconex (TN)
| Molecular Formula | C18H19Cl2N3O |
|---|---|
| Molecular Weight | 363.09 g/mol |
| LogP | 4.19 |
| Topological Polar Surface Area | 28.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 363.0905 |
| Heavy Atoms | 24 |
| Complexity | 450.0 |
Chemical Identifiers
| CAS Number | 54810-23-0 |
|---|---|
| SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.Cl |
| InChIKey | JSXBVMKACNEMKY-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Loxapine Hydrochloride (CAS 54810-23-0), with molecular formula C18H19Cl2N3O and molecular weight 363.09 g/mol. IUPAC: 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine;hydrochloride.
Chemical Property Profile of Loxapine Hydrochloride
Property Insights of Loxapine Hydrochloride
The XLogP value of 4.19 indicates that Loxapine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.1 Ų, Loxapine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Loxapine Hydrochloride has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Loxapine Hydrochloride?
The CAS number of Loxapine Hydrochloride is 54810-23-0.
What is the molecular formula of Loxapine Hydrochloride?
The molecular formula of Loxapine Hydrochloride is C18H19Cl2N3O.
What is the molecular weight of Loxapine Hydrochloride?
The molecular weight of Loxapine Hydrochloride is 363.09 g/mol.
Where can I buy Loxapine Hydrochloride?
You can request a quote for Loxapine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Loxapine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Loxapine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.