4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide
TL;DR: 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide (CAS 5459-64-3) is a chemical compound with molecular formula C21H14F2N2O2S and molecular weight 396.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide
Also Known As: 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide, T0520-5610, 4-(DIFLUOROMETHOXY)-N-[4-(NAPHTHALEN-2-YL)-1,3-THIAZOL-2-YL]BENZAMIDE
| Molecular Formula | C21H14F2N2O2S |
|---|---|
| Molecular Weight | 396.07 g/mol |
| LogP | 5.817 |
| Topological Polar Surface Area | 51.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 396.0744 |
| Heavy Atoms | 28 |
| Complexity | 1126.6807 |
Chemical Identifiers
| CAS Number | 5459-64-3 |
|---|---|
| SMILES | C1=CC=C2C=C(C=CC2=C1)C3=CSC(=N3)NC(=O)C4=CC=C(C=C4)OC(F)F |
Product Overview
4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide (CAS 5459-64-3), with molecular formula C21H14F2N2O2S and molecular weight 396.07 g/mol. IUPAC: 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide.
Chemical Property Profile of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide
Property Insights of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide
The XLogP value of 5.817 indicates that 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.22 Ų, 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide?
The CAS number of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide is 5459-64-3.
What is the molecular formula of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide?
The molecular formula of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide is C21H14F2N2O2S.
What is the molecular weight of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide?
The molecular weight of 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide is 396.07 g/mol.
Where can I buy 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide?
You can request a quote for 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide?
Yes, KEHONG BIO provides custom synthesis services for 4-(difluoromethoxy)-N-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.