Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate structure

Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate

TL;DR: Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate (CAS 5457-61-4) is a chemical compound with molecular formula C22H25NO3 and molecular weight 351.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 1-phenacyl-4-phenylpiperidine-4-carboxylate

Also Known As: Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate, ethyl 1-phenacyl-4-phenylpiperidine-4-carboxylate, ethyl 1-phenacyl-4-phenyl-piperidine-4-carboxylate, ISONIPECOTIC ACID, 1-PHENACYL-4-PHENYL-, ETHYL ESTER, 4-PIPERIDINECARBOXYLIC ACID, 1-(2-OXO-2-PHENYLETHYL)-4-PHENYL-, ETHYL ESTER

CAS: 5457-61-4
Molecular Formula C22H25NO3
Molecular Weight 351.18 g/mol
LogP 3.9
Topological Polar Surface Area 46.6 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 7
Exact Mass 351.18344
Heavy Atoms 26
Complexity 470.0

Chemical Identifiers

CAS Number 5457-61-4
SMILES CCOC(=O)C1(CCN(CC1)CC(=O)C2=CC=CC=C2)C3=CC=CC=C3
InChIKey XFKPHSMWBQJLCT-UHFFFAOYSA-N

Product Overview

Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate (CAS 5457-61-4), with molecular formula C22H25NO3 and molecular weight 351.18 g/mol. IUPAC: ethyl 1-phenacyl-4-phenylpiperidine-4-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate

XLogP
3.9
TPSA (Topological Polar Surface Area)
46.6
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
7
Heavy Atoms
26
Complexity
470.0
Exact Mass
351.18344
Monoisotopic Mass
351.18344
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate

The XLogP value of 3.9 indicates that Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.6 Ų, Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate?

The CAS number of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate is 5457-61-4.

What is the molecular formula of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate?

The molecular formula of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate is C22H25NO3.

What is the molecular weight of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate?

The molecular weight of Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate is 351.18 g/mol.

Where can I buy Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate?

You can request a quote for Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl 1-(2-oxo-2-phenylethyl)-4-phenyl-4-piperidinecarboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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