6-(Thiophen-2-yl)pyridazin-3(2H)-one structure

6-(Thiophen-2-yl)pyridazin-3(2H)-one

TL;DR: 6-(Thiophen-2-yl)pyridazin-3(2H)-one (CAS 54558-07-5) is a chemical compound with molecular formula C8H6N2OS and molecular weight 178.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-thiophen-2-yl-1H-pyridazin-6-one

Also Known As: 6-(thiophen-2-yl)pyridazin-3(2H)-one, 6-(2-THIENYL)-3(2H)-PYRIDAZINONE, 6-(thiophen-2-yl)pyridazin-3-ol, 6-(2-thienyl)pyridazin-3(2H)-one, ChemDiv3_014275

CAS: 54558-07-5
Molecular Formula C8H6N2OS
Molecular Weight 178.02 g/mol
LogP 1.4984
Topological Polar Surface Area 45.75 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 1
Exact Mass 178.02008
Heavy Atoms 12
Complexity 398.37784

Chemical Identifiers

CAS Number 54558-07-5
SMILES C1=CSC(=C1)C2=NNC(=O)C=C2

Product Overview

6-(Thiophen-2-yl)pyridazin-3(2H)-one (CAS 54558-07-5), with molecular formula C8H6N2OS and molecular weight 178.02 g/mol. IUPAC: 3-thiophen-2-yl-1H-pyridazin-6-one.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 6-(Thiophen-2-yl)pyridazin-3(2H)-one

XLogP
1.4984
TPSA (Topological Polar Surface Area)
45.75
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
12
Complexity
398.37784
Exact Mass
178.02008
Monoisotopic Mass
178.02008
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 6-(Thiophen-2-yl)pyridazin-3(2H)-one

The XLogP value of 1.4984 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-(Thiophen-2-yl)pyridazin-3(2H)-one. With a topological polar surface area (TPSA) of 45.75 Ų, 6-(Thiophen-2-yl)pyridazin-3(2H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(Thiophen-2-yl)pyridazin-3(2H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 6-(Thiophen-2-yl)pyridazin-3(2H)-one?

The CAS number of 6-(Thiophen-2-yl)pyridazin-3(2H)-one is 54558-07-5.

What is the molecular formula of 6-(Thiophen-2-yl)pyridazin-3(2H)-one?

The molecular formula of 6-(Thiophen-2-yl)pyridazin-3(2H)-one is C8H6N2OS.

What is the molecular weight of 6-(Thiophen-2-yl)pyridazin-3(2H)-one?

The molecular weight of 6-(Thiophen-2-yl)pyridazin-3(2H)-one is 178.02 g/mol.

Where can I buy 6-(Thiophen-2-yl)pyridazin-3(2H)-one?

You can request a quote for 6-(Thiophen-2-yl)pyridazin-3(2H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 6-(Thiophen-2-yl)pyridazin-3(2H)-one?

Yes, KEHONG BIO provides custom synthesis services for 6-(Thiophen-2-yl)pyridazin-3(2H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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