Rockogenin structure

Rockogenin

TL;DR: Rockogenin (CAS 5455-57-2) is a chemical compound with molecular formula C27H44O4 and molecular weight 432.32 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1R,2S,4S,5'R,6R,7S,8R,9S,10R,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-10,16-diol

Also Known As: Rockogenin, Rokogenin, Spirostan-3,12-diol, (25R)-5alpha-spirostan-3beta,12beta-diol, 5alpha,25alpha-Spirostan-3beta,12-diol

CAS: 5455-57-2
Molecular Formula C27H44O4
Molecular Weight 432.32 g/mol
LogP 5.1
Topological Polar Surface Area 58.9 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 0
Exact Mass 432.32397
Heavy Atoms 31
Complexity 726.0

Chemical Identifiers

CAS Number 5455-57-2
SMILES C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3([C@@H](C[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)O)C)O)C)C)OC1
InChIKey BQNMOLSYHYSCMS-TUUYSWIFSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (2 patents)

Product Overview

Rockogenin (CAS 5455-57-2), with molecular formula C27H44O4 and molecular weight 432.32 g/mol. IUPAC: (1R,2S,4S,5'R,6R,7S,8R,9S,10R,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-10,16-diol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Rockogenin

XLogP
5.1
TPSA (Topological Polar Surface Area)
58.9
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
0
Heavy Atoms
31
Complexity
726.0
Exact Mass
432.32397
Monoisotopic Mass
432.32397
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Rockogenin

The XLogP value of 5.1 indicates that Rockogenin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.9 Ų, Rockogenin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Rockogenin has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Rockogenin?

The CAS number of Rockogenin is 5455-57-2.

What is the molecular formula of Rockogenin?

The molecular formula of Rockogenin is C27H44O4.

What is the molecular weight of Rockogenin?

The molecular weight of Rockogenin is 432.32 g/mol.

Where can I buy Rockogenin?

You can request a quote for Rockogenin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Rockogenin?

Yes, KEHONG BIO provides custom synthesis services for Rockogenin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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