![(E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide structure](/static/products/5453/545349-64-2.webp)
(E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide
TL;DR: (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide (CAS 545349-64-2) is a chemical compound with molecular formula C19H18N4O3S2 and molecular weight 414.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide
Also Known As: (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide, N-(4-{[(2,6-dimethyl-4-pyrimidinyl)amino]sulfonyl}phenyl)-3-(2-thienyl)acrylamide, (2E)-N-{4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl}-3-(thiophen-2-yl)prop-2-enamide, (2E)-N-(4-{[(2,6-dimethylpyrimidin-4-yl)amino]sulfonyl}phenyl)-3-(2-thienyl)pr op-2-enamide
| Molecular Formula | C19H18N4O3S2 |
|---|---|
| Molecular Weight | 414.08 g/mol |
| LogP | 3.60764 |
| Topological Polar Surface Area | 101.05 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 414.08203 |
| Heavy Atoms | 28 |
| Complexity | 1086.3403 |
Chemical Identifiers
| CAS Number | 545349-64-2 |
|---|---|
| SMILES | CC1=CC(=NC(=N1)C)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)/C=C/C3=CC=CS3 |
Product Overview
(E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide (CAS 545349-64-2), with molecular formula C19H18N4O3S2 and molecular weight 414.08 g/mol. IUPAC: (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide
Property Insights of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide
The XLogP value of 3.60764 indicates that (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.05 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide. Following Lipinski's Rule of Five, (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide?
The CAS number of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide is 545349-64-2.
What is the molecular formula of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide?
The molecular formula of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide is C19H18N4O3S2.
What is the molecular weight of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide?
The molecular weight of (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide is 414.08 g/mol.
Where can I buy (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide?
You can request a quote for (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-[4-[(2,6-dimethylpyrimidin-4-yl)sulfamoyl]phenyl]-3-thiophen-2-ylprop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.