Olaparib Impurity 77
TL;DR: Olaparib Impurity 77 (CAS 545348-09-2) is a chemical compound with molecular formula C9H16N2O and molecular weight 168.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
cyclopropyl-(4-methylpiperazin-1-yl)methanone
Also Known As: Olaparib Impurity 77, Olaparib Impurity 104, Olaparib Impurity 114, cyclopropyl(4-methylpiperazin-1-yl)methanone, Cyclopropyl-(4-methylpiperazin-1-yl)methanone
| Molecular Formula | C9H16N2O |
|---|---|
| Molecular Weight | 168.13 g/mol |
| LogP | 0.1704 |
| Topological Polar Surface Area | 23.55 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 168.12627 |
| Heavy Atoms | 12 |
| Complexity | 180.96756 |
Chemical Identifiers
| CAS Number | 545348-09-2 |
|---|---|
| SMILES | CN1CCN(CC1)C(=O)C2CC2 |
Product Overview
Olaparib Impurity 77 (CAS 545348-09-2), with molecular formula C9H16N2O and molecular weight 168.13 g/mol. IUPAC: cyclopropyl-(4-methylpiperazin-1-yl)methanone.
Chemical Property Profile of Olaparib Impurity 77
Property Insights of Olaparib Impurity 77
The XLogP value of 0.1704 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Olaparib Impurity 77. With a topological polar surface area (TPSA) of 23.55 Ų, Olaparib Impurity 77 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Olaparib Impurity 77 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Olaparib Impurity 77?
The CAS number of Olaparib Impurity 77 is 545348-09-2.
What is the molecular formula of Olaparib Impurity 77?
The molecular formula of Olaparib Impurity 77 is C9H16N2O.
What is the molecular weight of Olaparib Impurity 77?
The molecular weight of Olaparib Impurity 77 is 168.13 g/mol.
Where can I buy Olaparib Impurity 77?
You can request a quote for Olaparib Impurity 77 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Olaparib Impurity 77?
Yes, KEHONG BIO provides custom synthesis services for Olaparib Impurity 77 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.