Jolkinolide E
TL;DR: Jolkinolide E (CAS 54494-34-7) is a chemical compound with molecular formula C20H28O2 and molecular weight 300.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4aR,10aR,11aR,11bR)-4,4,8,11b-tetramethyl-2,3,4a,5,6,10a,11,11a-octahydro-1H-naphtho[2,1-f][1]benzofuran-9-one
Also Known As: Jolkinolide E, jolkinolid E, HY-N7464, (4aR,10aR,11aR,11bR)-4,4,8,11b-tetramethyl-2,3,4a,5,6,10a,11,11a-octahydro-1H-naphtho[2,1-f][1]benzofuran-9-one, (4aR)-2,3,4,4aalpha,5,6,10abeta,11,11aalpha,11b-Decahydro-4,4,8,11bbeta-tetramethylphenanthro[3,2-b]furan-9(1H)-one
| Molecular Formula | C20H28O2 |
|---|---|
| Molecular Weight | 300.21 g/mol |
| LogP | 4.801 |
| Topological Polar Surface Area | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 300.20892 |
| Heavy Atoms | 22 |
| Complexity | 594.8285 |
Chemical Identifiers
| CAS Number | 54494-34-7 |
|---|---|
| SMILES | CC1=C2C=C3CC[C@H]4[C@]([C@@H]3C[C@H]2OC1=O)(CCCC4(C)C)C |
Product Overview
Jolkinolide E (CAS 54494-34-7), with molecular formula C20H28O2 and molecular weight 300.21 g/mol. IUPAC: (4aR,10aR,11aR,11bR)-4,4,8,11b-tetramethyl-2,3,4a,5,6,10a,11,11a-octahydro-1H-naphtho[2,1-f][1]benzofuran-9-one.
Chemical Property Profile of Jolkinolide E
Property Insights of Jolkinolide E
The XLogP value of 4.801 indicates that Jolkinolide E is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.3 Ų, Jolkinolide E exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Jolkinolide E has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Jolkinolide E?
The CAS number of Jolkinolide E is 54494-34-7.
What is the molecular formula of Jolkinolide E?
The molecular formula of Jolkinolide E is C20H28O2.
What is the molecular weight of Jolkinolide E?
The molecular weight of Jolkinolide E is 300.21 g/mol.
Where can I buy Jolkinolide E?
You can request a quote for Jolkinolide E directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Jolkinolide E?
Yes, KEHONG BIO provides custom synthesis services for Jolkinolide E and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.