3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide
TL;DR: 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide (CAS 544656-85-1) is a chemical compound with molecular formula C18H22N2OS and molecular weight 314.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)prop-2-enamide
Also Known As: 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide, (E)-3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)prop-2-enamide, (2E)-3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)prop-2-enamide, (E)-3-[4-(TERT-BUTYL)PHENYL]-N~1~-(4,5-DIMETHYL-1,3-THIAZOL-2-YL)-2-PROPENAMIDE
| Molecular Formula | C18H22N2OS |
|---|---|
| Molecular Weight | 314.15 g/mol |
| LogP | 4.70934 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 314.1453 |
| Heavy Atoms | 22 |
| Complexity | 671.3675 |
Chemical Identifiers
| CAS Number | 544656-85-1 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)/C=C/C2=CC=C(C=C2)C(C)(C)C)C |
Product Overview
3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide (CAS 544656-85-1), with molecular formula C18H22N2OS and molecular weight 314.15 g/mol. IUPAC: (E)-3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)prop-2-enamide.
Chemical Property Profile of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide
Property Insights of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide
The XLogP value of 4.70934 indicates that 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide?
The CAS number of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide is 544656-85-1.
What is the molecular formula of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide?
The molecular formula of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide is C18H22N2OS.
What is the molecular weight of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide?
The molecular weight of 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide is 314.15 g/mol.
Where can I buy 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide?
You can request a quote for 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for 3-(4-tert-butylphenyl)-N-(4,5-dimethyl-1,3-thiazol-2-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.