Nem-S-G
TL;DR: Nem-S-G (CAS 5446-05-9) is a chemical compound with molecular formula C16H22N4O8S and molecular weight 430.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-[2-(2,5-dioxopyrrol-1-yl)ethylsulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Also Known As: Nem-S-G, Ethyl maleimide-S-glutathione, N-Ethylmaleimide-S-glutathione, N-(S-(2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine, (2R)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-[2-(2,5-dioxopyrrol-1-yl)ethylsulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
| Molecular Formula | C16H22N4O8S |
|---|---|
| Molecular Weight | 430.12 g/mol |
| LogP | -4.9 |
| Topological Polar Surface Area | 222.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 13 |
| Exact Mass | 430.11584 |
| Heavy Atoms | 29 |
| Complexity | 693.0 |
Chemical Identifiers
| CAS Number | 5446-05-9 |
|---|---|
| SMILES | C1=CC(=O)N(C1=O)CCSC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@H](C(=O)O)N |
| InChIKey | VQDKPBCISILESC-ZJUUUORDSA-N |
Product Overview
Nem-S-G (CAS 5446-05-9), with molecular formula C16H22N4O8S and molecular weight 430.12 g/mol. IUPAC: (2R)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-[2-(2,5-dioxopyrrol-1-yl)ethylsulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid.
Chemical Property Profile of Nem-S-G
Property Insights of Nem-S-G
The XLogP value of -4.9 indicates that Nem-S-G is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 222.0 Ų indicates high polarity, suggesting Nem-S-G may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nem-S-G has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nem-S-G?
The CAS number of Nem-S-G is 5446-05-9.
What is the molecular formula of Nem-S-G?
The molecular formula of Nem-S-G is C16H22N4O8S.
What is the molecular weight of Nem-S-G?
The molecular weight of Nem-S-G is 430.12 g/mol.
Where can I buy Nem-S-G?
You can request a quote for Nem-S-G directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nem-S-G?
Yes, KEHONG BIO provides custom synthesis services for Nem-S-G and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.