Closiramine
TL;DR: Closiramine (CAS 5438-64-2) is a chemical compound with molecular formula C18H21ClN2 and molecular weight 300.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl)-N,N-dimethylethanamine
Also Known As: Closiramine, Closiramina, Closiraminum, Closiramine [INN], Closiraminum [INN-Latin]
| Molecular Formula | C18H21ClN2 |
|---|---|
| Molecular Weight | 300.14 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 16.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 300.1393 |
| Heavy Atoms | 21 |
| Complexity | 333.0 |
Chemical Identifiers
| CAS Number | 5438-64-2 |
|---|---|
| SMILES | CN(C)CCC1C2=C(CCC3=C1N=CC=C3)C=C(C=C2)Cl |
| InChIKey | BYUAWKXUYPHXSR-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Closiramine (CAS 5438-64-2), with molecular formula C18H21ClN2 and molecular weight 300.14 g/mol. IUPAC: 2-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl)-N,N-dimethylethanamine.
Chemical Property Profile of Closiramine
Property Insights of Closiramine
The XLogP value of 3.9 indicates that Closiramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 16.1 Ų, Closiramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Closiramine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Closiramine?
The CAS number of Closiramine is 5438-64-2.
What is the molecular formula of Closiramine?
The molecular formula of Closiramine is C18H21ClN2.
What is the molecular weight of Closiramine?
The molecular weight of Closiramine is 300.14 g/mol.
Where can I buy Closiramine?
You can request a quote for Closiramine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Closiramine?
Yes, KEHONG BIO provides custom synthesis services for Closiramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.