2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide
TL;DR: 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide (CAS 543721-72-8) is a chemical compound with molecular formula C12H7Cl2FN2O and molecular weight 283.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-(3-chloro-4-fluorophenyl)pyridine-3-carboxamide
Also Known As: 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide, 2-chloro-N-(3-chloro-4-fluorophenyl)pyridine-3-carboxamide
| Molecular Formula | C12H7Cl2FN2O |
|---|---|
| Molecular Weight | 283.99 g/mol |
| LogP | 3.7798 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 283.99194 |
| Heavy Atoms | 18 |
| Complexity | 604.38135 |
Chemical Identifiers
| CAS Number | 543721-72-8 |
|---|---|
| SMILES | C1=CC(=C(N=C1)Cl)C(=O)NC2=CC(=C(C=C2)F)Cl |
Product Overview
2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide (CAS 543721-72-8), with molecular formula C12H7Cl2FN2O and molecular weight 283.99 g/mol. IUPAC: 2-chloro-N-(3-chloro-4-fluorophenyl)pyridine-3-carboxamide.
Chemical Property Profile of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide
Property Insights of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide
The XLogP value of 3.7798 indicates that 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide?
The CAS number of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide is 543721-72-8.
What is the molecular formula of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide?
The molecular formula of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide is C12H7Cl2FN2O.
What is the molecular weight of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide?
The molecular weight of 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide is 283.99 g/mol.
Where can I buy 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide?
You can request a quote for 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-N-(3-chloro-4-fluorophenyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.