(E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide
TL;DR: (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide (CAS 543719-14-8) is a chemical compound with molecular formula C11H8FN3OS and molecular weight 249.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide
Also Known As: (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide, (2E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide, 3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)acrylamide
| Molecular Formula | C11H8FN3OS |
|---|---|
| Molecular Weight | 249.04 g/mol |
| LogP | 2.3291 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 249.03722 |
| Heavy Atoms | 17 |
| Complexity | 522.15936 |
Chemical Identifiers
| CAS Number | 543719-14-8 |
|---|---|
| SMILES | C1=CC(=CC=C1/C=C/C(=O)NC2=NN=CS2)F |
Product Overview
(E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide (CAS 543719-14-8), with molecular formula C11H8FN3OS and molecular weight 249.04 g/mol. IUPAC: (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide.
Chemical Property Profile of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide
Property Insights of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide
The XLogP value of 2.3291 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide. With a topological polar surface area (TPSA) of 54.88 Ų, (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide?
The CAS number of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide is 543719-14-8.
What is the molecular formula of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide?
The molecular formula of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide is C11H8FN3OS.
What is the molecular weight of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide?
The molecular weight of (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide is 249.04 g/mol.
Where can I buy (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide?
You can request a quote for (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(4-fluorophenyl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.