Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone
TL;DR: Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone (CAS 543705-18-6) is a chemical compound with molecular formula C18H16N2OS and molecular weight 308.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone
Also Known As: Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone, pyrrolidinyl 2-(2-thienyl)(4-quinolyl) ketone, pyrrolidin-1-yl[2-(thiophen-2-yl)quinolin-4-yl]methanone, 4-(PYRROLIDINE-1-CARBONYL)-2-(THIOPHEN-2-YL)QUINOLINE
| Molecular Formula | C18H16N2OS |
|---|---|
| Molecular Weight | 308.10 g/mol |
| LogP | 4.1993 |
| Topological Polar Surface Area | 33.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 308.09833 |
| Heavy Atoms | 22 |
| Complexity | 820.22925 |
Chemical Identifiers
| CAS Number | 543705-18-6 |
|---|---|
| SMILES | C1CCN(C1)C(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CS4 |
Product Overview
Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone (CAS 543705-18-6), with molecular formula C18H16N2OS and molecular weight 308.10 g/mol. IUPAC: pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone.
Chemical Property Profile of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone
Property Insights of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone
The XLogP value of 4.1993 indicates that Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 33.2 Ų, Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone?
The CAS number of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone is 543705-18-6.
What is the molecular formula of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone?
The molecular formula of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone is C18H16N2OS.
What is the molecular weight of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone?
The molecular weight of Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone is 308.10 g/mol.
Where can I buy Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone?
You can request a quote for Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for Pyrrolidin-1-yl-(2-thiophen-2-ylquinolin-4-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.