Trendione structure

Trendione

TL;DR: Trendione (CAS 5436-76-0) is a chemical compound with molecular formula C18H20O2 and molecular weight 268.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,13S,14S)-13-methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione

Also Known As: Trendione, Estra-4,9,11-triene-3,17-dione, TRENAVAR, Altrenogest impurity 10, Equilin Impurity 3; Trendione

CAS: 5436-76-0
Molecular Formula C18H20O2
Molecular Weight 268.15 g/mol
LogP 1.6
Topological Polar Surface Area 34.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 268.14633
Heavy Atoms 20
Complexity 605.0

Chemical Identifiers

CAS Number 5436-76-0
SMILES C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC2=O
InChIKey KBSXJBBFQODDTQ-RYRKJORJSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (6 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

Trendione (CAS 5436-76-0), with molecular formula C18H20O2 and molecular weight 268.15 g/mol. IUPAC: (8S,13S,14S)-13-methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Trendione

XLogP
1.6
TPSA (Topological Polar Surface Area)
34.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
20
Complexity
605.0
Exact Mass
268.14633
Monoisotopic Mass
268.14633
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Trendione

The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trendione. With a topological polar surface area (TPSA) of 34.1 Ų, Trendione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trendione has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Trendione?

The CAS number of Trendione is 5436-76-0.

What is the molecular formula of Trendione?

The molecular formula of Trendione is C18H20O2.

What is the molecular weight of Trendione?

The molecular weight of Trendione is 268.15 g/mol.

Where can I buy Trendione?

You can request a quote for Trendione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Trendione?

Yes, KEHONG BIO provides custom synthesis services for Trendione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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