5a,20a-Tetrahydroprogesterone
TL;DR: 5a,20a-Tetrahydroprogesterone (CAS 54353-11-6) is a chemical compound with molecular formula C21H34O2 and molecular weight 318.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
17-(1-hydroxyethyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Also Known As: 5a,20a-tetrahydroprogesterone, Allopregnan-20beta-ol-3-one, Allopregnan-20.beta.-ol-3-one, A-Pregnan-20, A-ol-3-one
| Molecular Formula | C21H34O2 |
|---|---|
| Molecular Weight | 318.26 g/mol |
| LogP | 4.8 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 318.2559 |
| Heavy Atoms | 23 |
| Complexity | 500.0 |
Chemical Identifiers
| CAS Number | 54353-11-6 |
|---|---|
| SMILES | CC(C1CCC2C1(CCC3C2CCC4C3(CCC(=O)C4)C)C)O |
| InChIKey | DYVGYXXLXQESJE-UHFFFAOYSA-N |
Product Overview
5a,20a-Tetrahydroprogesterone (CAS 54353-11-6), with molecular formula C21H34O2 and molecular weight 318.26 g/mol. IUPAC: 17-(1-hydroxyethyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 5a,20a-Tetrahydroprogesterone
Property Insights of 5a,20a-Tetrahydroprogesterone
The XLogP value of 4.8 indicates that 5a,20a-Tetrahydroprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 5a,20a-Tetrahydroprogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5a,20a-Tetrahydroprogesterone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5a,20a-Tetrahydroprogesterone?
The CAS number of 5a,20a-Tetrahydroprogesterone is 54353-11-6.
What is the molecular formula of 5a,20a-Tetrahydroprogesterone?
The molecular formula of 5a,20a-Tetrahydroprogesterone is C21H34O2.
What is the molecular weight of 5a,20a-Tetrahydroprogesterone?
The molecular weight of 5a,20a-Tetrahydroprogesterone is 318.26 g/mol.
Where can I buy 5a,20a-Tetrahydroprogesterone?
You can request a quote for 5a,20a-Tetrahydroprogesterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5a,20a-Tetrahydroprogesterone?
Yes, KEHONG BIO provides custom synthesis services for 5a,20a-Tetrahydroprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.