Estradiol 3-tetrahydropyranyl ether structure

Estradiol 3-tetrahydropyranyl ether

TL;DR: Estradiol 3-tetrahydropyranyl ether (CAS 54100-53-7) is a chemical compound with molecular formula C23H32O3 and molecular weight 356.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8R,9S,13S,14S,17S)-13-methyl-3-(oxan-2-yloxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

Also Known As: Estradiol 3-tetrahydropyranyl ether, Estradiol-3-tetrahydropyranylether, (17, A)-3-(tetrahydro-2h-pyran-2-yloxy)estra-1,3,5(10)-trien-17-ol, 17.beta.-Estradiol, 3-(tetrahydropyran-2-yl ether)

CAS: 54100-53-7
Molecular Formula C23H32O3
Molecular Weight 356.24 g/mol
LogP 3.9
Topological Polar Surface Area 38.7 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 356.23514
Heavy Atoms 26
Complexity 508.0

Chemical Identifiers

CAS Number 54100-53-7
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)OC5CCCCO5
InChIKey BOLMNLJKDBCJIB-CUFSGNDSSA-N

Product Overview

Estradiol 3-tetrahydropyranyl ether (CAS 54100-53-7), with molecular formula C23H32O3 and molecular weight 356.24 g/mol. IUPAC: (8R,9S,13S,14S,17S)-13-methyl-3-(oxan-2-yloxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Estradiol 3-tetrahydropyranyl ether

XLogP
3.9
TPSA (Topological Polar Surface Area)
38.7
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
26
Complexity
508.0
Exact Mass
356.23514
Monoisotopic Mass
356.23514
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Estradiol 3-tetrahydropyranyl ether

The XLogP value of 3.9 indicates that Estradiol 3-tetrahydropyranyl ether is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.7 Ų, Estradiol 3-tetrahydropyranyl ether exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Estradiol 3-tetrahydropyranyl ether has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Estradiol 3-tetrahydropyranyl ether?

The CAS number of Estradiol 3-tetrahydropyranyl ether is 54100-53-7.

What is the molecular formula of Estradiol 3-tetrahydropyranyl ether?

The molecular formula of Estradiol 3-tetrahydropyranyl ether is C23H32O3.

What is the molecular weight of Estradiol 3-tetrahydropyranyl ether?

The molecular weight of Estradiol 3-tetrahydropyranyl ether is 356.24 g/mol.

Where can I buy Estradiol 3-tetrahydropyranyl ether?

You can request a quote for Estradiol 3-tetrahydropyranyl ether directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Estradiol 3-tetrahydropyranyl ether?

Yes, KEHONG BIO provides custom synthesis services for Estradiol 3-tetrahydropyranyl ether and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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