Neoastilbin structure

Neoastilbin

TL;DR: Neoastilbin (CAS 54081-48-0) is a chemical compound with molecular formula C21H22O11 and molecular weight 450.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one

Also Known As: Neoastilbin, Isoastilbin, NEOSMITILBIN, Astilbin, (2S,3S)-Taxifolin 3-rhamnoside

CAS: 54081-48-0
Molecular Formula C21H22O11
Molecular Weight 450.12 g/mol
LogP 0.4
Topological Polar Surface Area 186.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 11
Rotatable Bonds 3
Exact Mass 450.1162
Heavy Atoms 32
Complexity 676.0

Chemical Identifiers

CAS Number 54081-48-0
SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2[C@@H](OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O
InChIKey ZROGCCBNZBKLEL-MFSALPCASA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (14 patents)

Product Overview

Neoastilbin (CAS 54081-48-0), with molecular formula C21H22O11 and molecular weight 450.12 g/mol. IUPAC: (2S,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Neoastilbin

XLogP
0.4
TPSA (Topological Polar Surface Area)
186.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
11
Rotatable Bonds
3
Heavy Atoms
32
Complexity
676.0
Exact Mass
450.1162
Monoisotopic Mass
450.1162
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Neoastilbin

The XLogP value of 0.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Neoastilbin. The TPSA of 186.0 Ų indicates high polarity, suggesting Neoastilbin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Neoastilbin has 7 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Neoastilbin?

The CAS number of Neoastilbin is 54081-48-0.

What is the molecular formula of Neoastilbin?

The molecular formula of Neoastilbin is C21H22O11.

What is the molecular weight of Neoastilbin?

The molecular weight of Neoastilbin is 450.12 g/mol.

Where can I buy Neoastilbin?

You can request a quote for Neoastilbin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Neoastilbin?

Yes, KEHONG BIO provides custom synthesis services for Neoastilbin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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