Toprilidine
TL;DR: Toprilidine (CAS 54063-58-0) is a chemical compound with molecular formula C19H25N3O and molecular weight 311.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2-methylphenyl)-4-(3-pyridin-2-yloxypropyl)piperazine
Also Known As: Toprilidine, Toprilidina, Toprilidinum, toprilidine[inn], Toprilidine [INN]
| Molecular Formula | C19H25N3O |
|---|---|
| Molecular Weight | 311.20 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 28.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 311.19977 |
| Heavy Atoms | 23 |
| Complexity | 331.0 |
Chemical Identifiers
| CAS Number | 54063-58-0 |
|---|---|
| SMILES | CC1=CC=CC=C1N2CCN(CC2)CCCOC3=CC=CC=N3 |
| InChIKey | CRXVPWCHOPXHMN-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Toprilidine (CAS 54063-58-0), with molecular formula C19H25N3O and molecular weight 311.20 g/mol. IUPAC: 1-(2-methylphenyl)-4-(3-pyridin-2-yloxypropyl)piperazine.
Chemical Property Profile of Toprilidine
Property Insights of Toprilidine
The XLogP value of 3.5 indicates that Toprilidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.6 Ų, Toprilidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Toprilidine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Toprilidine?
The CAS number of Toprilidine is 54063-58-0.
What is the molecular formula of Toprilidine?
The molecular formula of Toprilidine is C19H25N3O.
What is the molecular weight of Toprilidine?
The molecular weight of Toprilidine is 311.20 g/mol.
Where can I buy Toprilidine?
You can request a quote for Toprilidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Toprilidine?
Yes, KEHONG BIO provides custom synthesis services for Toprilidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.