Clobetasone
TL;DR: Clobetasone (CAS 54063-32-0) is a chemical compound with molecular formula C22H26ClFO4 and molecular weight 408.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione
Also Known As: Clobetasone, Clobetasona, Clobetasonum, Eumovate, Clobetasone (INN)
| Molecular Formula | C22H26ClFO4 |
|---|---|
| Molecular Weight | 408.15 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 71.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 408.15036 |
| Heavy Atoms | 28 |
| Complexity | 849.0 |
Chemical Identifiers
| CAS Number | 54063-32-0 |
|---|---|
| SMILES | C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3(C(=O)C[C@@]2([C@]1(C(=O)CCl)O)C)F)C |
| InChIKey | XXIFVOHLGBURIG-OZCCCYNHSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Clobetasone (CAS 54063-32-0), with molecular formula C22H26ClFO4 and molecular weight 408.15 g/mol. IUPAC: (8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione.
Chemical Property Profile of Clobetasone
Property Insights of Clobetasone
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Clobetasone. The TPSA of 71.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Clobetasone. Following Lipinski's Rule of Five, Clobetasone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clobetasone?
The CAS number of Clobetasone is 54063-32-0.
What is the molecular formula of Clobetasone?
The molecular formula of Clobetasone is C22H26ClFO4.
What is the molecular weight of Clobetasone?
The molecular weight of Clobetasone is 408.15 g/mol.
Where can I buy Clobetasone?
You can request a quote for Clobetasone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clobetasone?
Yes, KEHONG BIO provides custom synthesis services for Clobetasone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.