2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride structure

2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride

TL;DR: 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride (CAS 54001-22-8) is a chemical compound with molecular formula C11H7Cl2NOS and molecular weight 270.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(4-chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride

Also Known As: 2-(4-chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride, 5-chlorocarbonyl-2-(4-chlorophenyl)-4-methylthiazole, I14-86318, 2- -4-METHYL-1,3-THIAZOLE-5-CARBONYLCHLORIDE, 5-Thiazolecarbonylchloride, 2-(4-chlorophenyl)-4-methyl-

CAS: 54001-22-8
Molecular Formula C11H7Cl2NOS
Molecular Weight 270.96 g/mol
LogP 4.15092
Topological Polar Surface Area 29.96 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 270.96255
Heavy Atoms 16
Complexity 533.4176

Chemical Identifiers

CAS Number 54001-22-8
SMILES CC1=C(SC(=N1)C2=CC=C(C=C2)Cl)C(=O)Cl

Product Overview

2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride (CAS 54001-22-8), with molecular formula C11H7Cl2NOS and molecular weight 270.96 g/mol. IUPAC: 2-(4-chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride

XLogP
4.15092
TPSA (Topological Polar Surface Area)
29.96
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
16
Complexity
533.4176
Exact Mass
270.96255
Monoisotopic Mass
270.96255
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride

The XLogP value of 4.15092 indicates that 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.96 Ų, 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride?

The CAS number of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride is 54001-22-8.

What is the molecular formula of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride?

The molecular formula of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride is C11H7Cl2NOS.

What is the molecular weight of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride?

The molecular weight of 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride is 270.96 g/mol.

Where can I buy 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride?

You can request a quote for 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride?

Yes, KEHONG BIO provides custom synthesis services for 2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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