Nicophyllin structure

Nicophyllin

TL;DR: Nicophyllin (CAS 53890-71-4) is a chemical compound with molecular formula C15H21N7O4 and molecular weight 363.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1,3-dimethyl-7H-purine-2,6-dione;ethane-1,2-diamine;pyridine-3-carboxylic acid

Also Known As: Nicophyllin, Nicophylline, Nicofolina, 4-Nicotionylmorpholin, 1,3-dimethyl-7H-purine-2,6-dione;ethane-1,2-diamine;pyridine-3-carboxylic acid

CAS: 53890-71-4
Molecular Formula C15H21N7O4
Molecular Weight 363.17 g/mol
LogP -1.3561
Topological Polar Surface Area 172.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 8
Rotatable Bonds 2
Exact Mass 363.1655
Heavy Atoms 26
Complexity 387.0

Chemical Identifiers

CAS Number 53890-71-4
SMILES CN1C2=C(C(=O)N(C1=O)C)NC=N2.C1=CC(=CN=C1)C(=O)O.C(CN)N
InChIKey UPPYYQSTMLYYNF-UHFFFAOYSA-N

Product Overview

Nicophyllin (CAS 53890-71-4), with molecular formula C15H21N7O4 and molecular weight 363.17 g/mol. IUPAC: 1,3-dimethyl-7H-purine-2,6-dione;ethane-1,2-diamine;pyridine-3-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Nicophyllin

XLogP
-1.3561
TPSA (Topological Polar Surface Area)
172.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
8
Rotatable Bonds
2
Heavy Atoms
26
Complexity
387.0
Exact Mass
363.1655
Monoisotopic Mass
363.1655
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Nicophyllin

The XLogP value of -1.3561 indicates that Nicophyllin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 172.0 Ų indicates high polarity, suggesting Nicophyllin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nicophyllin has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Nicophyllin?

The CAS number of Nicophyllin is 53890-71-4.

What is the molecular formula of Nicophyllin?

The molecular formula of Nicophyllin is C15H21N7O4.

What is the molecular weight of Nicophyllin?

The molecular weight of Nicophyllin is 363.17 g/mol.

Where can I buy Nicophyllin?

You can request a quote for Nicophyllin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Nicophyllin?

Yes, KEHONG BIO provides custom synthesis services for Nicophyllin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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