Lonazolac
TL;DR: Lonazolac (CAS 53808-88-1) is a chemical compound with molecular formula C17H13ClN2O2 and molecular weight 312.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[3-(4-chlorophenyl)-1-phenylpyrazol-4-yl]acetic acid
Also Known As: Lonazolac, Lonazolaco, Lonazolacum, Irritren, Lonazolac [INN]
| Molecular Formula | C17H13ClN2O2 |
|---|---|
| Molecular Weight | 312.07 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 55.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 312.06656 |
| Heavy Atoms | 22 |
| Complexity | 379.0 |
Chemical Identifiers
| CAS Number | 53808-88-1 |
|---|---|
| SMILES | C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=C(C=C3)Cl)CC(=O)O |
| InChIKey | XVUQHFRQHBLHQD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lonazolac (CAS 53808-88-1), with molecular formula C17H13ClN2O2 and molecular weight 312.07 g/mol. IUPAC: 2-[3-(4-chlorophenyl)-1-phenylpyrazol-4-yl]acetic acid.
Chemical Property Profile of Lonazolac
Property Insights of Lonazolac
The XLogP value of 3.6 indicates that Lonazolac is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.1 Ų, Lonazolac exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lonazolac has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lonazolac?
The CAS number of Lonazolac is 53808-88-1.
What is the molecular formula of Lonazolac?
The molecular formula of Lonazolac is C17H13ClN2O2.
What is the molecular weight of Lonazolac?
The molecular weight of Lonazolac is 312.07 g/mol.
Where can I buy Lonazolac?
You can request a quote for Lonazolac directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lonazolac?
Yes, KEHONG BIO provides custom synthesis services for Lonazolac and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.