Substance P (4-11) structure

Substance P (4-11)

TL;DR: Substance P (4-11) (CAS 53749-60-3) is a chemical compound with molecular formula C46H67N11O10S and molecular weight 965.48 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]-2-(pyrrolidine-2-carbonylamino)pentanediamide

Also Known As: Substance P octapeptide, Substance P (4-11), SP(4-11), 1-Dearginyl-2-deprolyl-3-delysine-substance P, Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

CAS: 53749-60-3
Molecular Formula C46H67N11O10S
Molecular Weight 965.48 g/mol
LogP -0.1
Topological Polar Surface Area 370.0 Ų
Hydrogen Bond Donors 11
Hydrogen Bond Acceptors 12
Rotatable Bonds 30
Exact Mass 965.4793
Heavy Atoms 68
Complexity 1730.0

Chemical Identifiers

CAS Number 53749-60-3
SMILES CC(C)CC(C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)C3CCCN3
InChIKey XVTHVTVZLLFSPI-YJPQGOKNSA-N

Product Overview

Substance P (4-11) (CAS 53749-60-3), with molecular formula C46H67N11O10S and molecular weight 965.48 g/mol. IUPAC: (2S)-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]-2-(pyrrolidine-2-carbonylamino)pentanediamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Substance P (4-11)

XLogP
-0.1
TPSA (Topological Polar Surface Area)
370.0
Hydrogen Bond Donors
11
Hydrogen Bond Acceptors
12
Rotatable Bonds
30
Heavy Atoms
68
Complexity
1730.0
Exact Mass
965.4793
Monoisotopic Mass
965.4793
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Substance P (4-11)

The XLogP value of -0.1 indicates that Substance P (4-11) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 370.0 Ų indicates high polarity, suggesting Substance P (4-11) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Substance P (4-11) has 11 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Substance P (4-11)?

The CAS number of Substance P (4-11) is 53749-60-3.

What is the molecular formula of Substance P (4-11)?

The molecular formula of Substance P (4-11) is C46H67N11O10S.

What is the molecular weight of Substance P (4-11)?

The molecular weight of Substance P (4-11) is 965.48 g/mol.

Where can I buy Substance P (4-11)?

You can request a quote for Substance P (4-11) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Substance P (4-11)?

Yes, KEHONG BIO provides custom synthesis services for Substance P (4-11) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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