5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline
TL;DR: 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline (CAS 537033-70-8) is a chemical compound with molecular formula C11H7F4NO and molecular weight 245.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-6-methyl-2-(trifluoromethyl)-1H-quinolin-4-one
Also Known As: 5-fluoro-6-methyl-2-(trifluoromethyl)quinolin-4-ol, 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline, 5-fluoro-6-methyl-2-(trifluoromethyl)-1H-quinolin-4-one
| Molecular Formula | C11H7F4NO |
|---|---|
| Molecular Weight | 245.05 g/mol |
| LogP | 2.99442 |
| Topological Polar Surface Area | 32.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 245.04637 |
| Heavy Atoms | 17 |
| Complexity | 642.1871 |
Chemical Identifiers
| CAS Number | 537033-70-8 |
|---|---|
| SMILES | CC1=C(C2=C(C=C1)NC(=CC2=O)C(F)(F)F)F |
Product Overview
5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline (CAS 537033-70-8), with molecular formula C11H7F4NO and molecular weight 245.05 g/mol. IUPAC: 5-fluoro-6-methyl-2-(trifluoromethyl)-1H-quinolin-4-one.
Chemical Property Profile of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline
Property Insights of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline
The XLogP value of 2.99442 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline. With a topological polar surface area (TPSA) of 32.86 Ų, 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline?
The CAS number of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline is 537033-70-8.
What is the molecular formula of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline?
The molecular formula of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline is C11H7F4NO.
What is the molecular weight of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline?
The molecular weight of 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline is 245.05 g/mol.
Where can I buy 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline?
You can request a quote for 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline?
Yes, KEHONG BIO provides custom synthesis services for 5-Fluoro-4-hydroxy-6-methyl-2-(trifluoromethyl)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.