4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline
TL;DR: 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline (CAS 537033-68-4) is a chemical compound with molecular formula C11H7F4NO and molecular weight 245.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-fluoro-8-methoxy-2-(trifluoromethyl)quinoline
Also Known As: 4-fluoro-8-methoxy-2-(trifluoromethyl)quinoline
| Molecular Formula | C11H7F4NO |
|---|---|
| Molecular Weight | 245.05 g/mol |
| LogP | 3.4013 |
| Topological Polar Surface Area | 22.12 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 245.04637 |
| Heavy Atoms | 17 |
| Complexity | 565.1354 |
Chemical Identifiers
| CAS Number | 537033-68-4 |
|---|---|
| SMILES | COC1=CC=CC2=C1N=C(C=C2F)C(F)(F)F |
Product Overview
4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline (CAS 537033-68-4), with molecular formula C11H7F4NO and molecular weight 245.05 g/mol. IUPAC: 4-fluoro-8-methoxy-2-(trifluoromethyl)quinoline.
Chemical Property Profile of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline
Property Insights of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline
The XLogP value of 3.4013 indicates that 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 22.12 Ų, 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline?
The CAS number of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline is 537033-68-4.
What is the molecular formula of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline?
The molecular formula of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline is C11H7F4NO.
What is the molecular weight of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline?
The molecular weight of 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline is 245.05 g/mol.
Where can I buy 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline?
You can request a quote for 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline?
Yes, KEHONG BIO provides custom synthesis services for 4-Fluoro-8-methoxy-2-(trifluoromethyl)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.