Nefopam Hydrochloride
TL;DR: Nefopam Hydrochloride (CAS 53648-31-0) is a chemical compound with molecular formula C17H20ClNO and molecular weight 289.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride
Also Known As: Nefopam hydrochloride, Nefopam HCl, Acupan, nefopam, Pallopikeron
| Molecular Formula | C17H20ClNO |
|---|---|
| Molecular Weight | 289.12 g/mol |
| LogP | 3.6598 |
| Topological Polar Surface Area | 13.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 289.12335 |
| Heavy Atoms | 20 |
| Complexity | 274.0 |
| Solubility | >43.5 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 53648-31-0 |
|---|---|
| SMILES | CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3.Cl |
| InChIKey | CNNVSINJDJNHQK-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Nefopam Hydrochloride (CAS 53648-31-0), with molecular formula C17H20ClNO and molecular weight 289.12 g/mol. IUPAC: 5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride.
Chemical Property Profile of Nefopam Hydrochloride
Property Insights of Nefopam Hydrochloride
The XLogP value of 3.6598 indicates that Nefopam Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 13.7 Ų, Nefopam Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nefopam Hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nefopam Hydrochloride?
The CAS number of Nefopam Hydrochloride is 53648-31-0.
What is the molecular formula of Nefopam Hydrochloride?
The molecular formula of Nefopam Hydrochloride is C17H20ClNO.
What is the molecular weight of Nefopam Hydrochloride?
The molecular weight of Nefopam Hydrochloride is 289.12 g/mol.
Where can I buy Nefopam Hydrochloride?
You can request a quote for Nefopam Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nefopam Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Nefopam Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.