His-Glu structure

His-Glu

TL;DR: His-Glu (CAS 53634-28-9) is a chemical compound with molecular formula C11H16N4O5 and molecular weight 284.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]pentanedioic acid

Also Known As: His-Glu, H-His-Glu-OH, HE dipeptide, histidylglutamic acid, H-E Dipeptide

CAS: 53634-28-9
Molecular Formula C11H16N4O5
Molecular Weight 284.11 g/mol
LogP -1.2863
Topological Polar Surface Area 158.4 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 5
Rotatable Bonds 8
Exact Mass 284.11206
Heavy Atoms 20
Complexity 473.16785

Chemical Identifiers

CAS Number 53634-28-9
SMILES C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N

Product Overview

His-Glu (CAS 53634-28-9), with molecular formula C11H16N4O5 and molecular weight 284.11 g/mol. IUPAC: (2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]pentanedioic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of His-Glu

XLogP
-1.2863
TPSA (Topological Polar Surface Area)
158.4
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
5
Rotatable Bonds
8
Heavy Atoms
20
Complexity
473.16785
Exact Mass
284.11206
Monoisotopic Mass
284.11206
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of His-Glu

The XLogP value of -1.2863 indicates that His-Glu is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 158.4 Ų indicates high polarity, suggesting His-Glu may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, His-Glu has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of His-Glu?

The CAS number of His-Glu is 53634-28-9.

What is the molecular formula of His-Glu?

The molecular formula of His-Glu is C11H16N4O5.

What is the molecular weight of His-Glu?

The molecular weight of His-Glu is 284.11 g/mol.

Where can I buy His-Glu?

You can request a quote for His-Glu directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for His-Glu?

Yes, KEHONG BIO provides custom synthesis services for His-Glu and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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