1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline structure

1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline

TL;DR: 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline (CAS 535-86-4) is a chemical compound with molecular formula C17H17NO and molecular weight 251.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3,4-dihydro-2H-quinolin-1-yl-(4-methylphenyl)methanone

Also Known As: 1-(4-methylbenzoyl)-1,2,3,4-tetrahydroquinoline, KST-1A5522, (3,4-Dihydro-2H-quinolin-1-yl)-p-tolyl-methanone, BAS 00501601, BIM-0018438.P001

CAS: 535-86-4
Molecular Formula C17H17NO
Molecular Weight 251.13 g/mol
LogP 3.7
Topological Polar Surface Area 20.3 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 251.13101
Heavy Atoms 19
Complexity 319.0

Chemical Identifiers

CAS Number 535-86-4
SMILES CC1=CC=C(C=C1)C(=O)N2CCCC3=CC=CC=C32
InChIKey VZHRCTGZYLKICF-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (14 patents)

Product Overview

1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline (CAS 535-86-4), with molecular formula C17H17NO and molecular weight 251.13 g/mol. IUPAC: 3,4-dihydro-2H-quinolin-1-yl-(4-methylphenyl)methanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline

XLogP
3.7
TPSA (Topological Polar Surface Area)
20.3
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
19
Complexity
319.0
Exact Mass
251.13101
Monoisotopic Mass
251.13101
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline

The XLogP value of 3.7 indicates that 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.3 Ų, 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline?

The CAS number of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline is 535-86-4.

What is the molecular formula of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline?

The molecular formula of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline is C17H17NO.

What is the molecular weight of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline?

The molecular weight of 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline is 251.13 g/mol.

Where can I buy 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline?

You can request a quote for 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline?

Yes, KEHONG BIO provides custom synthesis services for 1-(4-Methylbenzoyl)-1,2,3,4-tetrahydroquinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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