2-Fluoro-5-(trifluoromethyl)aniline structure

2-Fluoro-5-(trifluoromethyl)aniline

TL;DR: 2-Fluoro-5-(trifluoromethyl)aniline (CAS 535-52-4) is a chemical compound with molecular formula C7H5F4N and molecular weight 179.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-fluoro-5-(trifluoromethyl)aniline

Also Known As: 2-Fluoro-5-(trifluoromethyl)aniline, 3-Amino-4-fluorobenzotrifluoride, 2-Fluoro-5-trifluoromethylaniline, alpha,alpha,alpha,6-Tetrafluoro-m-toluidine, 2-fluoro-5-trifluoromethylanilin

CAS: 535-52-4
Molecular Formula C7H5F4N
Molecular Weight 179.04 g/mol
LogP 2.5
Topological Polar Surface Area 26.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 0
Exact Mass 179.03581
Heavy Atoms 12
Complexity 156.0

Chemical Identifiers

CAS Number 535-52-4
SMILES C1=CC(=C(C=C1C(F)(F)F)N)F
InChIKey DRKWGMXFFCPZLW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (30 patents) Analytical Reagents (1 patents) Biotechnology (1 patents) Heterocyclic Building Blocks (178 patents) Organic Building Blocks (63 patents) +3 more

Product Overview

2-Fluoro-5-(trifluoromethyl)aniline (CAS 535-52-4), with molecular formula C7H5F4N and molecular weight 179.04 g/mol. IUPAC: 2-fluoro-5-(trifluoromethyl)aniline.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2-Fluoro-5-(trifluoromethyl)aniline

XLogP
2.5
TPSA (Topological Polar Surface Area)
26.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
0
Heavy Atoms
12
Complexity
156.0
Exact Mass
179.03581
Monoisotopic Mass
179.03581
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-Fluoro-5-(trifluoromethyl)aniline

The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Fluoro-5-(trifluoromethyl)aniline. With a topological polar surface area (TPSA) of 26.0 Ų, 2-Fluoro-5-(trifluoromethyl)aniline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Fluoro-5-(trifluoromethyl)aniline has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-Fluoro-5-(trifluoromethyl)aniline?

The CAS number of 2-Fluoro-5-(trifluoromethyl)aniline is 535-52-4.

What is the molecular formula of 2-Fluoro-5-(trifluoromethyl)aniline?

The molecular formula of 2-Fluoro-5-(trifluoromethyl)aniline is C7H5F4N.

What is the molecular weight of 2-Fluoro-5-(trifluoromethyl)aniline?

The molecular weight of 2-Fluoro-5-(trifluoromethyl)aniline is 179.04 g/mol.

Where can I buy 2-Fluoro-5-(trifluoromethyl)aniline?

You can request a quote for 2-Fluoro-5-(trifluoromethyl)aniline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-Fluoro-5-(trifluoromethyl)aniline?

Yes, KEHONG BIO provides custom synthesis services for 2-Fluoro-5-(trifluoromethyl)aniline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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