5-Iodo-L-histidine
TL;DR: 5-Iodo-L-histidine (CAS 5345-67-5) is a chemical compound with molecular formula C6H8IN3O2 and molecular weight 280.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-amino-3-(4-iodo-1H-imidazol-5-yl)propanoic acid
Also Known As: 5-Iodohistidine, 5-Iodo-L-histidine, monoiodohistidine, (3S)-3-(Trimethylsilyl)-2-pyrrolidinone, (2S)-2-amino-3-(4-iodo-1H-imidazol-5-yl)propanoic acid
| Molecular Formula | C6H8IN3O2 |
|---|---|
| Molecular Weight | 280.97 g/mol |
| LogP | -2.5 |
| Topological Polar Surface Area | 92.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 280.96613 |
| Heavy Atoms | 12 |
| Complexity | 178.0 |
Chemical Identifiers
| CAS Number | 5345-67-5 |
|---|---|
| SMILES | C1=NC(=C(N1)C[C@@H](C(=O)O)N)I |
| InChIKey | AAKROHZJMPGWQF-VKHMYHEASA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
5-Iodo-L-histidine (CAS 5345-67-5), with molecular formula C6H8IN3O2 and molecular weight 280.97 g/mol. IUPAC: (2S)-2-amino-3-(4-iodo-1H-imidazol-5-yl)propanoic acid.
Chemical Property Profile of 5-Iodo-L-histidine
Property Insights of 5-Iodo-L-histidine
The XLogP value of -2.5 indicates that 5-Iodo-L-histidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 92.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Iodo-L-histidine. Following Lipinski's Rule of Five, 5-Iodo-L-histidine has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Iodo-L-histidine?
The CAS number of 5-Iodo-L-histidine is 5345-67-5.
What is the molecular formula of 5-Iodo-L-histidine?
The molecular formula of 5-Iodo-L-histidine is C6H8IN3O2.
What is the molecular weight of 5-Iodo-L-histidine?
The molecular weight of 5-Iodo-L-histidine is 280.97 g/mol.
Where can I buy 5-Iodo-L-histidine?
You can request a quote for 5-Iodo-L-histidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Iodo-L-histidine?
Yes, KEHONG BIO provides custom synthesis services for 5-Iodo-L-histidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.