8-amino-6-fluoro-9-ribofuranosyl-9H-purine
TL;DR: 8-amino-6-fluoro-9-ribofuranosyl-9H-purine (CAS 5345-09-5) is a chemical compound with molecular formula C10H12FN5O4 and molecular weight 285.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,4S,5R)-2-(8-amino-6-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Also Known As: 6-Afrfp, 8-Amino-6-fluoro-9-ribofuranosyl-9H-purine, 6-fluoro-9-(d-ribofuranosyl)-9h-purin-8-amine, 6-Fluoro-9-beta-D-ribofuranosyl-9H-purin-8-amine, 9H-Purin-8-amine, 6-fluoro-9-beta-D-ribofuranosyl-
| Molecular Formula | C10H12FN5O4 |
|---|---|
| Molecular Weight | 285.09 g/mol |
| LogP | -0.6 |
| Topological Polar Surface Area | 140.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.08734 |
| Heavy Atoms | 20 |
| Complexity | 367.0 |
Chemical Identifiers
| CAS Number | 5345-09-5 |
|---|---|
| SMILES | C1=NC2=C(C(=N1)F)N=C(N2C3[C@@H]([C@@H]([C@H](O3)CO)O)O)N |
| InChIKey | XWHGSLXUVNOJEC-LZGMGDPASA-N |
Product Overview
8-amino-6-fluoro-9-ribofuranosyl-9H-purine (CAS 5345-09-5), with molecular formula C10H12FN5O4 and molecular weight 285.09 g/mol. IUPAC: (3R,4S,5R)-2-(8-amino-6-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol.
Chemical Property Profile of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine
Property Insights of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine
The XLogP value of -0.6 indicates that 8-amino-6-fluoro-9-ribofuranosyl-9H-purine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.0 Ų indicates high polarity, suggesting 8-amino-6-fluoro-9-ribofuranosyl-9H-purine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 8-amino-6-fluoro-9-ribofuranosyl-9H-purine has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine?
The CAS number of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine is 5345-09-5.
What is the molecular formula of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine?
The molecular formula of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine is C10H12FN5O4.
What is the molecular weight of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine?
The molecular weight of 8-amino-6-fluoro-9-ribofuranosyl-9H-purine is 285.09 g/mol.
Where can I buy 8-amino-6-fluoro-9-ribofuranosyl-9H-purine?
You can request a quote for 8-amino-6-fluoro-9-ribofuranosyl-9H-purine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-amino-6-fluoro-9-ribofuranosyl-9H-purine?
Yes, KEHONG BIO provides custom synthesis services for 8-amino-6-fluoro-9-ribofuranosyl-9H-purine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.