氟桂利嗪
TL;DR: 氟桂利嗪 (CAS 5343-57-7) is a chemical compound with molecular formula C26H26F2N2 and molecular weight 404.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氟桂利嗪
1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
Also Known As: flunarizine, Sibelium, Flunarizina, Flunarizinum, Flunarizin
| Molecular Formula | C26H26F2N2 |
|---|---|
| Molecular Weight | 404.21 g/mol |
| LogP | 5.3852 |
| Topological Polar Surface Area | 6.48 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 404.2064 |
| Heavy Atoms | 30 |
| Complexity | 899.0885 |
Chemical Identifiers
| CAS Number | 5343-57-7 |
|---|---|
| SMILES | C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F |
Product Overview
氟桂利嗪 (CAS 5343-57-7), with molecular formula C26H26F2N2 and molecular weight 404.21 g/mol. IUPAC: 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine.
Chemical Property Profile of 氟桂利嗪
Property Insights of 氟桂利嗪
The XLogP value of 5.3852 indicates that 氟桂利嗪 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.48 Ų, 氟桂利嗪 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 氟桂利嗪 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氟桂利嗪?
The CAS number of 氟桂利嗪 is 5343-57-7.
What is the molecular formula of 氟桂利嗪?
The molecular formula of 氟桂利嗪 is C26H26F2N2.
What is the molecular weight of 氟桂利嗪?
The molecular weight of 氟桂利嗪 is 404.21 g/mol.
Where can I buy 氟桂利嗪?
You can request a quote for 氟桂利嗪 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氟桂利嗪?
Yes, KEHONG BIO provides custom synthesis services for 氟桂利嗪 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.