![1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one structure](/static/products/533/53359-99-2.png)
1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one
TL;DR: 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one (CAS 53359-99-2) is a chemical compound with molecular formula C14H8F3N3O and molecular weight 291.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4-one
Also Known As: 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one, AJ-333/13050040, 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4-one
| Molecular Formula | C14H8F3N3O |
|---|---|
| Molecular Weight | 291.06 g/mol |
| LogP | 2.7995 |
| Topological Polar Surface Area | 47.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 291.06195 |
| Heavy Atoms | 21 |
| Complexity | 870.9575 |
Chemical Identifiers
| CAS Number | 53359-99-2 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C(F)(F)F)N2C=NC(=O)C3=C2N=CC=C3 |
Product Overview
1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one (CAS 53359-99-2), with molecular formula C14H8F3N3O and molecular weight 291.06 g/mol. IUPAC: 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4-one.
Chemical Property Profile of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one
Property Insights of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one
The XLogP value of 2.7995 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one. With a topological polar surface area (TPSA) of 47.78 Ų, 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one?
The CAS number of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one is 53359-99-2.
What is the molecular formula of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one?
The molecular formula of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one is C14H8F3N3O.
What is the molecular weight of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one?
The molecular weight of 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one is 291.06 g/mol.
Where can I buy 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one?
You can request a quote for 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1-[2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.