![2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile structure](/static/products/5321/5321-97-1.webp)
2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile
TL;DR: 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile (CAS 5321-97-1) is a chemical compound with molecular formula C17H10ClN3S and molecular weight 323.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-pyridin-3-ylprop-2-enenitrile
Also Known As: BAS 01279782, 2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile, AI-219/34612004, (Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-pyridin-3-ylprop-2-enenitrile, (2Z)-2-[4-(4-CHLOROPHENYL)-1,3-THIAZOL-2-YL]-3-(PYRIDIN-3-YL)PROP-2-ENENITRILE
| Molecular Formula | C17H10ClN3S |
|---|---|
| Molecular Weight | 323.03 g/mol |
| LogP | 4.92268 |
| Topological Polar Surface Area | 49.57 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 323.02838 |
| Heavy Atoms | 22 |
| Complexity | 845.6155 |
Chemical Identifiers
| CAS Number | 5321-97-1 |
|---|---|
| SMILES | C1=CC(=CN=C1)/C=C(/C#N)\C2=NC(=CS2)C3=CC=C(C=C3)Cl |
Product Overview
2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile (CAS 5321-97-1), with molecular formula C17H10ClN3S and molecular weight 323.03 g/mol. IUPAC: (Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-pyridin-3-ylprop-2-enenitrile.
Chemical Property Profile of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile
Property Insights of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile
The XLogP value of 4.92268 indicates that 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.57 Ų, 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile?
The CAS number of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile is 5321-97-1.
What is the molecular formula of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile?
The molecular formula of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile is C17H10ClN3S.
What is the molecular weight of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile?
The molecular weight of 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile is 323.03 g/mol.
Where can I buy 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile?
You can request a quote for 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for 2-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-(3-pyridinyl)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.