氟泼尼松龙
TL;DR: 氟泼尼松龙 (CAS 53-34-9) is a chemical compound with molecular formula C21H27FO5 and molecular weight 378.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氟泼尼松龙
6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Also Known As: fluprednisolone, Alphadrol, Isopredon, Vladicort, Etadrol
| Molecular Formula | C21H27FO5 |
|---|---|
| Molecular Weight | 378.18 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.18427 |
| Heavy Atoms | 27 |
| Complexity | 760.0 |
Chemical Identifiers
| CAS Number | 53-34-9 |
|---|---|
| SMILES | CC12CC(C3C(C1CCC2(C(=O)CO)O)CC(C4=CC(=O)C=CC34C)F)O |
| InChIKey | MYYIMZRZXIQBGI-UHFFFAOYSA-N |
Product Overview
氟泼尼松龙 (CAS 53-34-9), with molecular formula C21H27FO5 and molecular weight 378.18 g/mol. IUPAC: 6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 氟泼尼松龙
Property Insights of 氟泼尼松龙
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 氟泼尼松龙. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 氟泼尼松龙. Following Lipinski's Rule of Five, 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione?
The CAS number of 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione is 53-34-9.
What is the molecular formula of 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione?
The molecular formula of 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione is C21H27FO5.
What is the molecular weight of 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione?
The molecular weight of 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione is 378.18 g/mol.
Where can I buy 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione?
You can request a quote for 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione?
Yes, KEHONG BIO provides custom synthesis services for 6alpha-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.