Proflazepam
TL;DR: Proflazepam (CAS 52829-30-8) is a chemical compound with molecular formula C18H16ClFN2O3 and molecular weight 362.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-1-(2,3-dihydroxypropyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one
Also Known As: Proflazepam, Proflazepam [INN], 7-chloro-1-(2,3-dihydroxypropyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one, 7-chloro-1-(2,3-dihydroxypropyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-Chloro-1-(2,3-dihydroxypropyl)-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
| Molecular Formula | C18H16ClFN2O3 |
|---|---|
| Molecular Weight | 362.08 g/mol |
| LogP | 2.0163 |
| Topological Polar Surface Area | 73.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 362.08334 |
| Heavy Atoms | 25 |
| Complexity | 840.8209 |
Chemical Identifiers
| CAS Number | 52829-30-8 |
|---|---|
| SMILES | C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CC(CO)O |
Product Overview
Proflazepam (CAS 52829-30-8), with molecular formula C18H16ClFN2O3 and molecular weight 362.08 g/mol. IUPAC: 7-chloro-1-(2,3-dihydroxypropyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one.
Chemical Property Profile of Proflazepam
Property Insights of Proflazepam
The XLogP value of 2.0163 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Proflazepam. The TPSA of 73.13 Ų falls within the moderate polarity range, balancing permeability and solubility for Proflazepam. Following Lipinski's Rule of Five, Proflazepam has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Proflazepam?
The CAS number of Proflazepam is 52829-30-8.
What is the molecular formula of Proflazepam?
The molecular formula of Proflazepam is C18H16ClFN2O3.
What is the molecular weight of Proflazepam?
The molecular weight of Proflazepam is 362.08 g/mol.
Where can I buy Proflazepam?
You can request a quote for Proflazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Proflazepam?
Yes, KEHONG BIO provides custom synthesis services for Proflazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.