Galgravin structure

Galgravin

TL;DR: Galgravin (CAS 528-63-2) is a chemical compound with molecular formula C22H28O5 and molecular weight 372.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2R,3R,4S,5S)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane

Also Known As: Galgravin, Veraguensin, Galbelgin, ganschisandrine, (-)-galgravin

CAS: 528-63-2
Molecular Formula C22H28O5
Molecular Weight 372.19 g/mol
LogP 4.4
Topological Polar Surface Area 46.2 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 372.19366
Heavy Atoms 27
Complexity 418.0

Chemical Identifiers

CAS Number 528-63-2
SMILES C[C@@H]1[C@@H]([C@H](O[C@H]1C2=CC(=C(C=C2)OC)OC)C3=CC(=C(C=C3)OC)OC)C
InChIKey JLJAVUZBHSLLJL-DQEHQXCCSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (3 patents)

Product Overview

Galgravin (CAS 528-63-2), with molecular formula C22H28O5 and molecular weight 372.19 g/mol. IUPAC: (2R,3R,4S,5S)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Galgravin

XLogP
4.4
TPSA (Topological Polar Surface Area)
46.2
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
27
Complexity
418.0
Exact Mass
372.19366
Monoisotopic Mass
372.19366
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Galgravin

The XLogP value of 4.4 indicates that Galgravin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.2 Ų, Galgravin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Galgravin has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Galgravin?

The CAS number of Galgravin is 528-63-2.

What is the molecular formula of Galgravin?

The molecular formula of Galgravin is C22H28O5.

What is the molecular weight of Galgravin?

The molecular weight of Galgravin is 372.19 g/mol.

Where can I buy Galgravin?

You can request a quote for Galgravin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Galgravin?

Yes, KEHONG BIO provides custom synthesis services for Galgravin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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