3'-Fluorothymidine-5'-triphosphate
TL;DR: 3'-Fluorothymidine-5'-triphosphate (CAS 52777-93-2) is a chemical compound with molecular formula C10H16FN2O13P3 and molecular weight 483.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Also Known As: FdTTP, 3-FddTTP, FLT-TP, 3'-Fluorothymidine-5'-triphosphate, 3'-FddTTP
| Molecular Formula | C10H16FN2O13P3 |
|---|---|
| Molecular Weight | 483.98 g/mol |
| LogP | -3.6 |
| Topological Polar Surface Area | 218.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 8 |
| Exact Mass | 483.98492 |
| Heavy Atoms | 29 |
| Complexity | 858.0 |
Chemical Identifiers
| CAS Number | 52777-93-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)F |
| InChIKey | UNKRRBWXJZNMAN-XLPZGREQSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
3'-Fluorothymidine-5'-triphosphate (CAS 52777-93-2), with molecular formula C10H16FN2O13P3 and molecular weight 483.98 g/mol. IUPAC: [[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate.
Chemical Property Profile of 3'-Fluorothymidine-5'-triphosphate
Property Insights of 3'-Fluorothymidine-5'-triphosphate
The XLogP value of -3.6 indicates that 3'-Fluorothymidine-5'-triphosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 218.0 Ų indicates high polarity, suggesting 3'-Fluorothymidine-5'-triphosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3'-Fluorothymidine-5'-triphosphate has 5 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Fluorothymidine-5'-triphosphate?
The CAS number of 3'-Fluorothymidine-5'-triphosphate is 52777-93-2.
What is the molecular formula of 3'-Fluorothymidine-5'-triphosphate?
The molecular formula of 3'-Fluorothymidine-5'-triphosphate is C10H16FN2O13P3.
What is the molecular weight of 3'-Fluorothymidine-5'-triphosphate?
The molecular weight of 3'-Fluorothymidine-5'-triphosphate is 483.98 g/mol.
Where can I buy 3'-Fluorothymidine-5'-triphosphate?
You can request a quote for 3'-Fluorothymidine-5'-triphosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Fluorothymidine-5'-triphosphate?
Yes, KEHONG BIO provides custom synthesis services for 3'-Fluorothymidine-5'-triphosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.