2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone
TL;DR: 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone (CAS 527751-50-4) is a chemical compound with molecular formula C14H10ClFO2 and molecular weight 264.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-chlorophenyl)-1-(5-fluoro-2-hydroxyphenyl)ethanone
Also Known As: 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone, 2-(2-chlorophenyl)-1-(5-fluoro-2-hydroxyphenyl)ethanone, 2-(2-chlorophenyl)-1-(5-fluoro-2-hydroxy-phenyl)ethanone, 2-(2-chlorophenyl)-1-(5-fluoro-2-hydroxyphenyl)ethan-1-one
| Molecular Formula | C14H10ClFO2 |
|---|---|
| Molecular Weight | 264.04 g/mol |
| LogP | 3.6101 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 264.03534 |
| Heavy Atoms | 18 |
| Complexity | 596.0979 |
Chemical Identifiers
| CAS Number | 527751-50-4 |
|---|---|
| SMILES | C1=CC=C(C(=C1)CC(=O)C2=C(C=CC(=C2)F)O)Cl |
Product Overview
2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone (CAS 527751-50-4), with molecular formula C14H10ClFO2 and molecular weight 264.04 g/mol. IUPAC: 2-(2-chlorophenyl)-1-(5-fluoro-2-hydroxyphenyl)ethanone.
Chemical Property Profile of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone
Property Insights of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone
The XLogP value of 3.6101 indicates that 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone?
The CAS number of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone is 527751-50-4.
What is the molecular formula of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone?
The molecular formula of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone is C14H10ClFO2.
What is the molecular weight of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone?
The molecular weight of 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone is 264.04 g/mol.
Where can I buy 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone?
You can request a quote for 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone?
Yes, KEHONG BIO provides custom synthesis services for 2-(2-Chlorophenyl)-5'-fluoro-2'-hydroxyacetophenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.