3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin structure

3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin

TL;DR: 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin (CAS 527751-40-2) is a chemical compound with molecular formula C16H10ClFO2 and molecular weight 288.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(3-chlorophenyl)-6-fluoro-4-methylchromen-2-one

Also Known As: 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin, 3-(3-chlorophenyl)-6-fluoro-4-methylchromen-2-one, 3-(3-chlorophenyl)-6-fluoro-4-methyl-chromen-2-one

CAS: 527751-40-2
Molecular Formula C16H10ClFO2
Molecular Weight 288.04 g/mol
LogP 4.56092
Topological Polar Surface Area 30.21 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 288.03534
Heavy Atoms 20
Complexity 867.97015

Chemical Identifiers

CAS Number 527751-40-2
SMILES CC1=C(C(=O)OC2=C1C=C(C=C2)F)C3=CC(=CC=C3)Cl

Product Overview

3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin (CAS 527751-40-2), with molecular formula C16H10ClFO2 and molecular weight 288.04 g/mol. IUPAC: 3-(3-chlorophenyl)-6-fluoro-4-methylchromen-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin

XLogP
4.56092
TPSA (Topological Polar Surface Area)
30.21
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
20
Complexity
867.97015
Exact Mass
288.03534
Monoisotopic Mass
288.03534
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin

The XLogP value of 4.56092 indicates that 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.21 Ų, 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin?

The CAS number of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin is 527751-40-2.

What is the molecular formula of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin?

The molecular formula of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin is C16H10ClFO2.

What is the molecular weight of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin?

The molecular weight of 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin is 288.04 g/mol.

Where can I buy 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin?

You can request a quote for 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin?

Yes, KEHONG BIO provides custom synthesis services for 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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