Tioperidone structure

Tioperidone

TL;DR: Tioperidone (CAS 52618-67-4) is a chemical compound with molecular formula C25H32N4O2S and molecular weight 452.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[4-[4-(2-propylsulfanylphenyl)piperazin-1-yl]butyl]-1H-quinazoline-2,4-dione

Also Known As: Tioperidone, Tioperidone [INN], Tioperidona, TIOPERIDONE HYDROCHLORIDE, 3-[4-[4-(2-propylsulfanylphenyl)piperazin-1-yl]butyl]-1H-quinazoline-2,4-dione

CAS: 52618-67-4
Molecular Formula C25H32N4O2S
Molecular Weight 452.22 g/mol
LogP 4.4
Topological Polar Surface Area 81.2 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 9
Exact Mass 452.2246
Heavy Atoms 32
Complexity 625.0

Chemical Identifiers

CAS Number 52618-67-4
SMILES CCCSC1=CC=CC=C1N2CCN(CC2)CCCCN3C(=O)C4=CC=CC=C4NC3=O
InChIKey CDNFCUXEJDEBEX-UHFFFAOYSA-N

Product Overview

Tioperidone (CAS 52618-67-4), with molecular formula C25H32N4O2S and molecular weight 452.22 g/mol. IUPAC: 3-[4-[4-(2-propylsulfanylphenyl)piperazin-1-yl]butyl]-1H-quinazoline-2,4-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tioperidone

XLogP
4.4
TPSA (Topological Polar Surface Area)
81.2
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
9
Heavy Atoms
32
Complexity
625.0
Exact Mass
452.2246
Monoisotopic Mass
452.2246
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tioperidone

The XLogP value of 4.4 indicates that Tioperidone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Tioperidone. Following Lipinski's Rule of Five, Tioperidone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tioperidone?

The CAS number of Tioperidone is 52618-67-4.

What is the molecular formula of Tioperidone?

The molecular formula of Tioperidone is C25H32N4O2S.

What is the molecular weight of Tioperidone?

The molecular weight of Tioperidone is 452.22 g/mol.

Where can I buy Tioperidone?

You can request a quote for Tioperidone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tioperidone?

Yes, KEHONG BIO provides custom synthesis services for Tioperidone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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