![2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine structure](/static/products/5246/524674-06-4.webp)
2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine
TL;DR: 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine (CAS 524674-06-4) is a chemical compound with molecular formula C11H11ClF3N and molecular weight 249.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-chloro-3-(trifluoromethyl)phenyl]pyrrolidine
Also Known As: 2-[4-chloro-3-(trifluoromethyl)phenyl]pyrrolidine
| Molecular Formula | C11H11ClF3N |
|---|---|
| Molecular Weight | 249.05 g/mol |
| LogP | 3.7833 |
| Topological Polar Surface Area | 12.03 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 249.0532 |
| Heavy Atoms | 16 |
| Complexity | 383.30634 |
Chemical Identifiers
| CAS Number | 524674-06-4 |
|---|---|
| SMILES | C1CC(NC1)C2=CC(=C(C=C2)Cl)C(F)(F)F |
Product Overview
2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine (CAS 524674-06-4), with molecular formula C11H11ClF3N and molecular weight 249.05 g/mol. IUPAC: 2-[4-chloro-3-(trifluoromethyl)phenyl]pyrrolidine.
Chemical Property Profile of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine
Property Insights of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine
The XLogP value of 3.7833 indicates that 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.03 Ų, 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine?
The CAS number of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine is 524674-06-4.
What is the molecular formula of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine?
The molecular formula of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine is C11H11ClF3N.
What is the molecular weight of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine?
The molecular weight of 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine is 249.05 g/mol.
Where can I buy 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine?
You can request a quote for 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine?
Yes, KEHONG BIO provides custom synthesis services for 2-[4-Chloro-3-(trifluoromethyl)phenyl]pyrrolidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.